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From Halopedia, the Halo wiki
The SPARTAN-II augmentation procedures were a series of biochemical and bio-mechanical manipulations applied to SPARTAN-II conscripts at the onset of puberty. Human biochemical experiments and enhancement procedures have been a part of society dating back to the 20th Century; their gains have attracted widespread attention in the hopes of improving human strength and endurance. Military experimentation of such enhancements however, has always been limited for morale's sake and ethical concerns.
