Editing Project ASTER

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Chemical augmentations work on a molecular level by targeting molecules within the body and then altering them to begin a growth process of targeted tissues. Although the chemicals work on a molecular level, they do not work on a genetic level, as targeted mutagenesis is impossible using chemicals alone.
Chemical augmentations work on a molecular level by targeting molecules within the body and then altering them to begin a growth process of targeted tissues. Although the chemicals work on a molecular level, they do not work on a genetic level, as targeted mutagenesis is impossible using chemicals alone.


The process of augmenting the SPARTAN-IIs was divided into two parts, surgical procedures and injection procedures. Surgeries were highly risky, intensive, and required special medical talent. Their safety and effects varied substantially from subject to subject, with the benefits and risks varying with the surgeon, the surgical conditions, and the state of the patient.<ref name="pariah2">'''[[Halo: Evolutions - Essential Tales of the Halo Universe]]''' '''[[Pariah]]''' ''page 32''</ref> Chemical augmentations have their own risks dependent upon the subject's genetic background and how they adjust to the alteration of cells and molecules and to a more physical point, tissue growth. SPARTAN-IIs also underwent extensive gene therapy.<ref>'''[[Halo: The Fall of Reach - The Animated Series]]'''</ref> In addition, the ASTER augmentation routine also replaced a number of organs.{{Ref/Book|Id=Enc22|Enc22|Page=67}}
The process of augmenting the SPARTAN-IIs was divided into two parts, surgical procedures and injection procedures. Surgeries were highly risky, intensive, and required special medical talent. Their safety and effects varied substantially from subject to subject, with the benefits and risks varying with the surgeon, the surgical conditions, and the state of the patient.<ref name="pariah2">'''[[Halo: Evolutions - Essential Tales of the Halo Universe]]''' '''[[Pariah]]''' ''page 32''</ref> Chemical augmentations have their own risks dependent upon the subject's genetic background and how they adjust to the alteration of cells and molecules and to a more physical point, tissue growth. SPARTAN-IIs also underwent extensive gene therapy.<ref>'''[[Halo: The Fall of Reach - The Animated Series]]'''</ref>
{| class="wikitable"
{| class="wikitable"
! Procedure
! Procedure
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|-
|-
|Carbide Ceramic Ossification
|Carbide Ceramic Ossification
|The candidate's bones are exposed via surgery or procedurally sequential surgeries. An advanced carbide ceramic material is grafted onto the skeletal structure to begin assimilation into the upper layers of each individual bone. This results in the bones being virtually unbreakable. The coverage of this procedure does not exceed 3% total bone mass due to significant white blood cell necrosis: effectively, the carbide ceramic can only comprise a thin outer "shell" bonded to each bone without interfering with bone functionality as organs.<ref name ="reach"/>
|The candidate's bones are exposed via surgery or procedurally sequential surgeries. An advanced carbide ceramic material is grafted onto the skeletal structure to begin assimilation into the upper layers of the each individual bone. This results in the bones being virtually unbreakable. The coverage of this procedure does not exceed 3% total bone mass due to significant white blood cell necrosis: effectively, the carbide ceramic can only comprise a thin outer "shell" bonded to each bone without interfering with bone functionality as organs.<ref name ="reach"/>
|3.8% failure rate due to possible mutations and compromised bone marrow matrix integrity. In pre-and near-postpubescent adolescents, skeletal growth spurts may cause irreparable bone pulverization.<ref name ="reach"/><ref name ="halsey1"/>
|3.8% failure rate due to possible mutations and compromised bone marrow matrix integrity. In pre-and near-postpubescent adolescents, skeletal growth spurts may cause irreparable bone pulverization.<ref name ="reach"/><ref name ="halsey1"/>
|-
|-
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==Procedure==
==Procedure==
<!--The following is based on the information provided in both The Fall of Reach and Pariah in Halo Evolutions. The information provided in this section is as accurate as can possibly be, using what sources are available and by research done.-->
<!--The following is based on the information provided in both The Fall of Reach and Pariah in Halo Evolutions. The information provided in this section is as accurate as can possibly be, using what sources are available and by research done.-->
[[File:S-II's awaiting augmentation.png|thumb|300px|Candidates awaiting augmentation procedures.]]
[[File:S-II's awaiting augmentation.png|thumb|right|300px|Candidates awaiting augmentation procedures.]]
To prepare the subject for the augmentation procedure, the subject's head is shaved and incision vectors are [[laser]]ed onto the subject's body. An intravenous drip is inserted into the subject's arm, and a general anaesthetic is administered to ease the subject into a state of unconsciousness. Once the subject has been sedated, he or she is transported from the pre-op wing of the facility to another area where the surgical procedures are performed.<ref>'''Halo: The Fall of Reach''' ''page 59'' (2001 edition) ''page 66'' (definitive edition) ''page 77'' (2010 edition)</ref>
To prepare the subject for the augmentation procedure, the subject's head is shaved and incision vectors are [[laser]]ed onto the subject's body. An intravenous drip is inserted into the subject's arm, and a general anaesthetic is administered to ease the subject into a state of unconsciousness. Once the subject has been sedated, he or she is transported from the pre-op wing of the facility to another area where the surgical procedures are performed.<ref>'''Halo: The Fall of Reach''' ''page 59'' (2001 edition) ''page 66'' (definitive edition) ''page 77'' (2010 edition)</ref>


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===Effects===
===Effects===
[[File:S-II Augmentation - Negative Side-effects.png|thumb|300px|[[SPARTAN-013]] experiencing the negative side-effects of augmentation, resulting in his death.]]
[[File:S-II Augmentation - Negative Side-effects.png|thumb|right|300px|[[SPARTAN-073]] experiencing the negative side-effects of augmentation, resulting in his death.]]
Although the subject is in a state of unconsciousness during the procedure, they may experience excruciating pain. Physiological stress brought on by the augmentations can produce cardiac arrest,<ref name ="halsey1"/> in addition to cross-chemical complications that can result in augmentation failure.
Although the subject is in a state of unconsciousness during the procedure, they may experience excruciating pain. Physiological stress brought on by the augmentations can produce cardiac arrest,<ref name ="halsey1"/> in addition to cross-chemical complications that can result in augmentation failure.


Each procedure is marked by a particular type of excruciating pain. The carbide ceramic ossification is said to feel like the subject's bones are breaking, and as if their marrow is made of glass and is being shattered.<ref name="onyx">'''[[Halo: Ghosts of Onyx]]''', ''page 63''</ref><ref name="ghost">'''Halo: Ghosts of Onyx''', ''page 101-102''</ref> The catalytic thyroid implant and muscular enhancement injections produce extraordinary pain, as if the subject's veins had been "injected with napalm";{{Ref/Reuse|pariah}}{{Ref/Reuse|ghost}} another sensation is pulsating and the feeling of the veins being torn out of the subject's skin. The effect of the muscles increasing in density is said to make the subject feel like their entire body is on fire, mixed with the feeling of "plated glass shattering" and being worked in the subject's body.{{Ref/Reuse|pariah}} The superconducting fibrification of neural dendrites is said to feel like fire burning along the subject's spinal nerves.{{Ref/Reuse|onyx}}  
Each procedure is marked by a particular type of excruciating pain. The carbide ceramic ossification is said to feel like the subject's bones are breaking, and as if their marrow is made of glass and is being shattered.<ref name="onyx">'''[[Halo: Ghosts of Onyx]]''', ''page 63''</ref><ref name="ghost">'''Halo: Ghosts of Onyx''', ''page 101-102''</ref> The catalytic thyroid implant and muscular enhancement injections produce extraordinary pain, as if the subject's veins had been "injected with napalm";{{Ref/Reuse|pariah}}{{Ref/Reuse|ghost}} another sensation is pulsating and the feeling of the veins being torn out of the subject's skin. The effect of the muscles increasing in density is said to make the subject feel like their entire body is on fire, mixed with the feeling of "plated glass shattering" and being worked in the subject's body.{{Ref/Reuse|pariah}} The superconducting fabrication of neural dendrites is said to feel like fire burning along the subject's spinal nerves.{{Ref/Reuse|onyx}}  


The side effects of completing the augmentations vary, as the subject's brain relearns how to move their body with faster reflexes and stronger muscles. The subject may experience neurological confusion such as falling over, exaggerated reflexes, and problems grabbing or holding onto an object. The subject may experience bleeding from the eyes, constant headaches, and aches in the bones.<ref>'''Halo: Fall of Reach''', ''page 62'' (2001 edition) ''page 69'' (definitive edition) ''page 80'' (2010 edition)</ref>  
The side effects of completing the augmentations vary, as the subject's brain relearns how to move their body with faster reflexes and stronger muscles. The subject may experience neurological confusion such as falling over, exaggerated reflexes, and problems grabbing or holding onto an object. The subject may experience bleeding from the eyes, constant headaches, and aches in the bones.<ref>'''Halo: Fall of Reach''', ''page 62'' (2001 edition) ''page 69'' (definitive edition) ''page 80'' (2010 edition)</ref>  

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