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| {{Status|Canon}} | | {{Era|ILB}} |
| [[File:Daisies - Homecoming.png|thumb|300px|[[Daisy-023]] confronts her flash clone, using a wheelchair due to metabolic cascade failure.]]
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| {{quote|Doctor speak for 'Everything falls apart.'|[[Kamal Zaman]]{{Ref/Reuse|ilb}}}} | | {{quote|Doctor speak for 'Everything falls apart.'|[[Kamal Zaman]]}} |
| '''Metabolic cascade failure''' is a medical condition suffered by [[Flash cloning|flash cloned]] [[human]] beings.<ref name="ilb">'''[[Axon Clips Chapter 3]]''', ''[[Media:ILB_Your_fault.ogg|ILB_Your_fault.ogg]]''</ref> It is a series of neurological diseases that occur in short succession, typically rendering the human dead within the span of a year. Metabolic cascade failure is the eventual fate of the majority of flash clones, although a select few are projected to live a normal lifespan. Because human flash clones are grown a hundred times faster than natural-born humans (hence the name), many anomalies appear. The clones lack the [[Wikipedia:muscle memory|muscle memory]] and [[Wikipedia:socialization|socialization]] of their hosts. While these problems can be remedied with intensive therapy, compounding biological defects cannot be corrected. Rapid flash cloning of such immense volumes of tissue induces gross DNA base-pair errors; congenital defects increase 42 percent and incidents of [[Wikipedia:Parkinson's disease|Parkinson's]]-plus syndromes increase 67 percent. The average half-life of a human flash clone is 14.7 weeks in laboratory conditions.<ref>'''[[Dr. Halsey's personal journal]]''', ''September 8, 2511''</ref>
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| Most of the clones used to replace the [[SPARTAN-II]] children succumbed to this condition. Contrary to Dr. [[Catherine Halsey]]'s expectations, many of the clones lived far longer than previously estimated based on laboratory conditions,<ref>'''Dr. Halsey's personal journal''', ''December 24, 2517''</ref> with at least four surviving until [[2525]].<ref>'''Halo Legends''' - ''[[Homecoming]]''</ref>
| | '''Metabolic Cascade Failure''' is a medical condition suffered by [[humans]] and primarily [[Flash Clones]]. It is a series of neurological diseases that occur in short succession, rendering the human dead within the span of a year. While it does occur in natural humans, Metabolic Cascade Failure is the eventual fate of all flash clones. |
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| ==Trivia==
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| While the biological degeneration of the SPARTAN-II flash clones is described in multiple sources, the condition is only identified as "metabolic cascade failure" in ''[[i love bees]]''.
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| ==List of appearances==
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| *''[[Halo: The Fall of Reach]]'' {{Fm}}
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| *''[[i love bees]]'' {{C|First identified as "metabolic cascade failure"}}
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| *''[[Halo Legends]]''
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| **''[[Homecoming]]''
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| *''[[Halo: Reach]]''
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| **''[[Dr. Halsey's personal journal]]'' {{Mo}}
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| *''[[Halo: Glasslands]]'' {{Mo}}
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| *''[[Halo: The Thursday War]]'' {{Mo}}
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| *''[[Halo: Mortal Dictata]]'' {{Mo}}
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| *''[[Hunt the Truth]]'' {{Mo}}
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| ==Sources==
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| {{Ref/Sources}}
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| | ==References== |
| | <references/> |
| [[Category:Diseases]] | | [[Category:Diseases]] |
| | [[Category:I Love Bees]] |
